The Bluestar bus was full of youngsters some of whom have been injured. Barton Peveril college has issued a statement confirming the bus was carrying students.
Parents are being direct to a parent hub where they can collect their child once cleared to leave.
Three “high priority” patients have been taken to hospital, South Central Ambulance Service said.
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A spokesperson said: “We have sent multiple units to the incident including five ambulances, two helicopters, and specialist response units.
“We’re continuing to support and assess patients on scene. All patients have been removed from the bus. Three high priority patients are being taken to hospital. Around 14 with less serious injuries are being treated on scene.”
“Access is being restricted to the cordoned area while youngsters are being treated.
An incident command has been set up on scene.
A Barton Peveril college statement said: “We are aware of an incident involving the College 607 Bus. College staff are working closely with the police to ensure the safety and well-being of all students.
“We ask that people do not attend the actual scene. For concerned parents, an Incident Centre has been established at The Hub at Bishopstoke.
“An officer and College staff will be available at the Hub to provide updates and address any questions you may have.”